Mulanje (MJ) District hospital continues to dispose their waste in Polopoto river as such the quality of water decreases. People around MJ hospital market and Njedza are concerned the most because they are unable to use the water for either irrigation or other purposes. This is due to improper waste disposal from the hospital such as plastics and municipal waste water among others that contribute to the contamination of the river. Polluter Pays Principle should be imposed on the district hospital and the council because they are all aware of the incident and are trained on proper waste disposal and the impact it has on environment. The river must be treated before the water borne diseases are transferred into Likhubula River where Polopoto ends.